Recurrent pregnancy loss treatment

Recurrent Pregnancy Loss Treatment in Ahmedabad

Dr. Ladu Dewasi provides specialist evaluation and individualised treatment for couples who have experienced two or more pregnancy losses. As a consultant gynaecologist and infertility specialist consulting at Mayflower Women’s Hospital, Bopal, Ahmedabad, Dr. Ladu Dewasi investigates possible underlying causes, explains what current evidence does and does not support, and builds a care plan suited to your specific history, whether that means targeted medical treatment, correction of a structural issue, fertility treatment, or ongoing support when no clear cause is found.
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Understanding Recurrent Pregnancy Loss

Recurrent pregnancy loss (RPL) is commonly defined as two or more pregnancy losses. Some guidelines use this two-loss threshold to begin evaluation, while others, particularly in the UK, require three losses for a formal diagnosis. The exact threshold applied, and the timing of evaluation, can vary between guidelines and individual clinical circumstances, so your specialist will consider the details of your own pregnancy history when deciding whether further evaluation is appropriate.
Miscarriage on its own is common, and a single loss does not usually indicate an underlying problem. Repeated losses are what typically prompt a fuller evaluation.

When Should You See a Specialist?

Consider a specialist evaluation if you have had:

  • Two or more pregnancy losses, whether confirmed by ultrasound or a positive pregnancy test
  • A pregnancy loss after the first trimester
  • Pregnancy loss alongside a known condition such as thyroid disease, PCOS or a clotting disorder
  • Significant anxiety about trying again without understanding possible causes

An evaluation can identify a treatable cause where one exists and, just as importantly, can offer reassurance and a monitoring plan when no clear cause is found.

Possible Causes of Recurrent Pregnancy Loss

Not every factor below applies to every patient, and in many couples, no single cause is ever identified. Your evaluation will help determine which, if any, apply to you.

  • Genetic and chromosomal factors — most early pregnancy losses relate to chromosomal abnormalities in the embryo, which become more common with age. Less commonly, one partner carries a chromosomal rearrangement that does not affect their own health but can lead to imbalanced embryos.
  • Uterine and structural factors — conditions that distort the uterine cavity, such as a uterine septum, polyps or submucosal fibroids, can interfere with implantation and may be among the more treatable causes.
  • Hormonal and endocrine factors — thyroid disorders and PCOS may be associated with pregnancy loss and may be assessed as part of an appropriate work-up.
  • Antiphospholipid syndrome (APS) — an autoimmune condition associated with increased clotting risk and recurrent pregnancy loss. It is diagnosed using specific blood tests and, when confirmed, treatment during pregnancy may include low-dose aspirin and/or heparin under specialist supervision.
  • Maternal age — the likelihood of chromosomal abnormalities in the embryo, and therefore miscarriage, increases with maternal age, particularly from the mid-to-late 30s onward.
  • Other medical conditions — such as poorly controlled diabetes, may be assessed as part of a broader evaluation, depending on your individual history.
  • Lifestyle and environmental factors — smoking, high alcohol intake and certain environmental exposures have been associated with increased pregnancy-loss risk in some studies. Optimising relevant lifestyle factors is part of appropriate preconception care.
  • Unexplained recurrent pregnancy loss — in some couples, no clear cause is identified even after appropriate evaluation. This does not mean nothing can be done. Your specialist can discuss supportive care, pregnancy planning and evidence-based options for a future pregnancy.

How Is Recurrent Pregnancy Loss Evaluated?

Evaluation begins with a detailed discussion of your medical and pregnancy history, including the timing, number and nature of previous losses, followed by an examination where appropriate. Based on this information, Dr. Dewasi will recommend specific investigations rather than a fixed, one-size-fits-all panel.

Tests That May Be Considered for Recurrent Pregnancy Loss

Depending on your history, your specialist may discuss:

  • Parental karyotyping — a blood test from both partners to check for chromosomal rearrangements
  • Uterine cavity assessment — using ultrasound, saline infusion sonohysterography or hysteroscopy
  • Antiphospholipid antibody testing — including lupus anticoagulant, anticardiolipin antibodies and anti-β2-glycoprotein I
  • Thyroid function tests
  • Testing of pregnancy tissue, where available, from a prior loss

Not every patient needs every test. Broad immunological panels, such as NK-cell activity or cytokine testing, are not recommended as routine RPL evaluation by major reproductive medicine societies, because current evidence does not support their routine use for guiding treatment. Dr. Dewasi will explain the reasoning behind any test she does or does not recommend for you.

Recurrent Pregnancy Loss Treatment and Management

Treatment is guided by what your evaluation finds and by what current evidence supports.
  • Antiphospholipid syndrome: If this is confirmed, it’s usually managed with low-dose aspirin and/or a blood thinner (heparin) during pregnancy, under close specialist supervision.
  • Structural uterine abnormalities: Things like polyps, fibroids, or a uterine septum can often be corrected with a minor procedure called hysteroscopy. Because Dr. Ladu Dewasi also holds an MD in Anaesthesia, she personally manages your sedation during the procedure, a reassurance for patients who feel anxious about anaesthesia, or who have a condition like asthma or thyroid disease that needs careful planning. The exact approach depends on the size, type, and location of the issue.
  • Chromosomal rearrangements: If either partner is found to carry one, you’ll be offered genetic counselling to understand what it means and what your options are.
  • Thyroid or hormonal imbalances: These are treated medically, based on the specific condition identified.
  • Progesterone support: This may be recommended in certain cases. Evidence and dosing vary, so it’s tailored to you rather than given routinely to everyone.
  • Preconception optimisation: This can include things like reaching a healthy weight, quitting smoking, cutting back on alcohol, and managing any existing health conditions.
  • Fertility treatment (IUI or IVF/ICSI with genetic testing): This may be discussed in select cases, depending on your specific diagnosis and history, it’s not a default step for everyone.

Can IVF Help With Recurrent Pregnancy Loss?

IVF is not a routine or universal treatment for recurrent pregnancy loss and is not necessary for every couple. It may be relevant in specific situations, such as when there is a separate infertility diagnosis or certain genetic circumstances. Current evidence does not show that IVF with embryo genetic testing shortens the time to a successful pregnancy for couples with recurrent pregnancy loss who are not otherwise infertile. The decision should therefore be made individually, based on your full medical and reproductive history.

What to Expect at Your Recurrent Pregnancy Loss Consultation

  1. Detailed discussion of your medical and pregnancy history
  2. Review of previous reports, scans or pathology results
  3. Identification of possible risk factors
  4. Recommended investigations tailored to your individual history
  5. Diagnosis and assessment once relevant results are available
  6. A personalised management plan discussed together
  7. Follow-up and early pregnancy monitoring, where appropriate

What to Bring to Your Recurrent Pregnancy Loss Consultation

  • Dates and details of previous pregnancies and losses, including gestational age at the time of each loss, where known
  • Previous test, scan and pathology reports, where available
  • A list of current medications and supplements
  • Details of known medical conditions such as thyroid disease, PCOS or clotting disorders
  • Relevant personal or family medical history

Take the Next Step Toward a Healthy Pregnancy

Get a personalised evaluation for recurrent pregnancy loss with Dr. Ladu Dewasi in Bopal, Ahmedabad.
Book an Appointment

Recurrent Pregnancy Loss Care with Dr. Ladu Dewasi

Dr. Ladu Dewasi is a consultant gynaecologist and infertility specialist with over seven years of experience in gynaecology, obstetrics and reproductive medicine, consulting at Mayflower Women’s Hospital, Bopal, Ahmedabad. She holds an MBBS and an MD in Anaesthesia, a dual qualification that means procedures such as hysteroscopy can be performed with her personally planning and managing sedation, rather than delegating this to a separate team.
Her approach to recurrent pregnancy loss is evaluation-led: recommending tests based on individual history rather than a standard panel, and explaining clearly where evidence for a particular test or treatment is strong and where it remains limited.

Visiting Dr. Ladu Dewasi's Clinic in Bopal, Ahmedabad

Dr. Ladu Dewasi consults at Mayflower Women’s Hospital, 2nd Floor, Satyamev Elite, Bopal–Ambli Junction, Sardar Patel Ring Road, Bopal, Ahmedabad 380058.
Call or WhatsApp: +91 9909716716

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Frequently Asked Questions

Recurrent pregnancy loss is commonly defined as two or more pregnancy losses. Some guidelines use two losses as the threshold to begin evaluation, while others require three for a formal diagnosis — the exact approach can vary between guidelines and individual clinical circumstances.
Possible causes include chromosomal abnormalities, uterine structural issues, antiphospholipid syndrome, thyroid disorders and other medical or hormonal factors. In some couples, no specific cause is identified even after appropriate evaluation.
Depending on your history, testing may include parental karyotyping, assessment of the uterine cavity, antiphospholipid antibody testing and thyroid function tests. Testing of pregnancy tissue may also be considered when available and appropriate. Not every patient needs every test.
Treatment depends on the underlying cause. Some identified causes can be treated or managed, while couples with unexplained recurrent pregnancy loss may receive supportive care, pregnancy monitoring and individualised guidance.
IVF is not a routine or universal treatment for recurrent pregnancy loss. It may be considered in selected situations, including when there is a separate infertility diagnosis or certain genetic circumstances. The decision should be individualised.
Depending on your history, testing may include parental karyotyping, assessment of the uterine cavity, antiphospholipid antibody testing and thyroid function tests. Testing of pregnancy tissue may also be considered when available and appropriate. Not every patient needs every test.
Treatment depends on the underlying cause. Some identified causes can be treated or managed, while couples with unexplained recurrent pregnancy loss may receive supportive care, pregnancy monitoring and individualised guidance.
IVF is not a routine or universal treatment for recurrent pregnancy loss. It may be considered in selected situations, including when there is a separate infertility diagnosis or certain genetic circumstances. The decision should be individualised.
Yes. The likelihood of chromosomal abnormalities in the embryo, and the risk of miscarriage, increases with maternal age, particularly from the mid-to-late 30s onward.
Many people who experience recurrent pregnancy loss go on to have successful pregnancies. Individual outlook depends on factors such as age, medical history and whether an underlying cause is identified. Your specialist can discuss your individual situation and appropriate follow-up.

Mayflower Women’s Hospital – 2nd Floor, Satyamev Elite Ambli, Junction, Sardar Patel Ring Rd, Bopal, Ahmedabad, Gujarat 380058

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